USMLE Prep - Medical Reference Library

SJS/TEN — Burn Unit Management

System: Burn Surgery • Reviewed: Aug 31, 2025 • Step 1Step 2Step 3

Synopsis:

Manage SJS/TEN in a burn unit: stop culprit drugs, aggressive supportive care (fluids, temperature, nutrition), wound care like partial‑thickness burns, and consider immunomodulators per protocol.

Key Points

  • Stabilize ABCs; begin targeted evaluation without delaying life-saving therapy.
  • Use system-specific risk tools to guide testing and disposition.
  • Order high-yield tests first; escalate imaging when indicated.
  • Start evidence-based initial therapy and reassess frequently.

Algorithm

  1. Primary survey and vitals; IV access and monitors.
  2. Focused history/physical; identify red flags and likely etiologies.
  3. Order system-appropriate labs and imaging (see Investigations).
  4. Initiate guideline-based empiric therapy (see Pharmacology).
  5. Reassess response; arrange consultation and definitive management.

Clinical Synopsis & Reasoning

For Burn Surgery Stevens Johnson Ten Management In Burn Unit, frame the differential by acuity and pathophysiology, then align diagnostics to the leading hypotheses. Prioritize stabilization while obtaining high‑yield studies such as CBC (Baseline hematology), BMP (Electrolytes/renal). Incorporate bedside imaging and targeted labs to define severity and identify complications; synthesize results with clinical trajectory to refine the working diagnosis and disposition needs.


Treatment Strategy & Disposition

Initiate disease‑directed therapy alongside supportive care, titrating to objective response. Pharmacologic options commonly include Analgesia/Antipyretics. Use validated frameworks (e.g., SCORTEN Variables) to guide escalation and site of care. Address precipitating factors, de‑escalate empiric therapies with data, and arrange follow‑up for monitoring and risk‑factor modification; admit patients with instability, high risk of deterioration, or needs for close monitoring.


Management Notes

Eye care is time‑sensitive—early amniotic membrane in severe ocular disease. Provide detailed allergy documentation at discharge.


Epidemiology / Risk Factors

  • Risk factors vary by condition and patient profile

Investigations

TestRole / RationaleTypical FindingsNotes
CBCBaseline hematologyAbnormal counts
BMPElectrolytes/renalDerangements

SCORTEN Variables

VariablePresence
Age >40
HR >120
Cancer
% Detachment >10%
BUN >10 mmol/L

Pharmacology

MedicationMechanismOnsetRole in TherapyLimitations
Silver sulfadiazine (topical)AntimicrobialHoursPartial-thickness burnsLeukopenia; sulfa allergy
AnalgesicsPain controlMinutesBurn painSedation
Tetanus prophylaxisVaccine/IG per statusHoursAs indicatedLocal rxn

Prognosis / Complications

  • Prognosis depends on severity, comorbidities, and timeliness of care

Patient Education / Counseling

  • Explain red flags and when to seek emergent care.
  • Reinforce medication adherence and follow-up plan.

References

  1. SJS/TEN Burn Unit — Link