USMLE Prep - Medical Reference Library

Gross Hematuria with Clot Retention - Three Way Catheter and Irrigation

System: Urology • Reviewed: Aug 31, 2025 • Step 1Step 2Step 3

Synopsis:

Manage hemodynamics, place a large three way catheter, evacuate clots, begin continuous bladder irrigation, and address anticoagulation and source control.

Key Points

  • Stabilize ABCs; begin targeted evaluation without delaying life-saving therapy.
  • Use system-specific risk tools to guide testing and disposition.
  • Order high-yield tests first; escalate imaging when indicated.
  • Start evidence-based initial therapy and reassess frequently.

Algorithm

  1. Primary survey and vitals; IV access and monitors.
  2. Focused history/physical; identify red flags and likely etiologies.
  3. Order system-appropriate labs and imaging (see Investigations).
  4. Initiate guideline-based empiric therapy (see Pharmacology).
  5. Reassess response; arrange consultation and definitive management.

Clinical Synopsis & Reasoning

For Gross Hematuria Clot Retention Three Way Irrigation, frame the differential by acuity and pathophysiology, then align diagnostics to the leading hypotheses. Prioritize stabilization while obtaining high‑yield studies such as CBC (Baseline hematology), BMP (Electrolytes/renal). Incorporate bedside imaging and targeted labs to define severity and identify complications; synthesize results with clinical trajectory to refine the working diagnosis and disposition needs.


Treatment Strategy & Disposition

Initiate disease‑directed therapy alongside supportive care, titrating to objective response. Pharmacologic options commonly include Analgesia/Antipyretics. Use validated frameworks (e.g., Catheter Options) to guide escalation and site of care. Address precipitating factors, de‑escalate empiric therapies with data, and arrange follow‑up for monitoring and risk‑factor modification; admit patients with instability, high risk of deterioration, or needs for close monitoring.


Epidemiology / Risk Factors

  • Risk factors vary by condition and patient profile

Investigations

TestRole / RationaleTypical FindingsNotes
CBCBaseline hematologyAbnormal counts
BMPElectrolytes/renalDerangements

Catheter Options

SizeUse
22 to 24 FrenchTypical for clot evacuation
Larger sizes as neededSevere bleeding or clots
Coude tipOutlet obstruction

Pharmacology

MedicationMechanismOnsetRole in TherapyLimitations
TXA (selected)AntifibrinolyticHoursGross hematuria clot retentionThrombosis risk

Prognosis / Complications

  • Prognosis depends on severity, comorbidities, and timeliness of care

Patient Education / Counseling

  • Explain red flags and when to seek emergent care.
  • Reinforce medication adherence and follow-up plan.

Notes

Use isotonic irrigation fluid. Monitor bladder pressure and avoid over distension.


References

  1. AUA Hematuria resources — Link
  2. EAU Urological Trauma and Hematuria guidance — Link