USMLE Prep - Medical Reference Library

Dyspnea — Use of POCUS (BLUE Protocol) in ED

System: Emergency Medicine • Reviewed: Aug 31, 2025 • Step 1Step 2Step 3

Synopsis:

The BLUE protocol uses lung ultrasound profiles to differentiate causes of acute dyspnea (A‑profile, B‑profile, A’/B’ with DVT, PLAPS). Rapidly narrows diagnosis at bedside.

Key Points

  • Stabilize ABCs; begin targeted evaluation without delaying life-saving therapy.
  • Use system-specific risk tools to guide testing and disposition.
  • Order high-yield tests first; escalate imaging when indicated.
  • Start evidence-based initial therapy and reassess frequently.

Algorithm

  1. Primary survey and vitals; IV access and monitors.
  2. Focused history/physical; identify red flags and likely etiologies.
  3. Order system-appropriate labs and imaging (see Investigations).
  4. Initiate guideline-based empiric therapy (see Pharmacology).
  5. Reassess response; arrange consultation and definitive management.

Clinical Synopsis & Reasoning

For Dyspnea Use Of Pocus Blue Protocol In Ed, frame the differential by acuity and pathophysiology, then align diagnostics to the leading hypotheses. Prioritize stabilization while obtaining high‑yield studies such as CBC/BMP (Baseline labs), CXR/targeted imaging (Common ED complaints), Troponin/EKG (chest pain) (ACS rule-out). Incorporate bedside imaging and targeted labs to define severity and identify complications; synthesize results with clinical trajectory to refine the working diagnosis and disposition needs.


Treatment Strategy & Disposition

Initiate disease‑directed therapy alongside supportive care, titrating to objective response. Pharmacologic options commonly include Analgesics, Antiemetics. Use validated frameworks (e.g., Profiles & Likely Dx) to guide escalation and site of care. Address precipitating factors, de‑escalate empiric therapies with data, and arrange follow‑up for monitoring and risk‑factor modification; admit patients with instability, high risk of deterioration, or needs for close monitoring.


Management Notes

Practice standardized probe positions. Save clips to the chart. Correlate with history and vitals.


Epidemiology / Risk Factors

  • Varies by presentation; age/comorbidities matter

Investigations

TestRole / RationaleTypical FindingsNotes
CBC/BMPBaseline labsAbnormalities
CXR/targeted imagingCommon ED complaintsFindings vary
Troponin/EKG (chest pain)ACS rule-outMI changesUse risk tools

Profiles & Likely Dx

ProfileDiagnosis
A + DVTPulmonary embolism
B bilateralCardiogenic pulmonary edema
A’ (no sliding)Pneumothorax (if lung point)
PLAPSPneumonia/effusion
C profileAnterolateral consolidation (pneumonia)

Pharmacology

MedicationMechanismOnsetRole in TherapyLimitations
AcetaminophenAnalgesic/antipyreticHoursSymptom control as appropriateHepatotoxicity (overdose)
Ondansetron5-HT3 antagonismMinutesAntiemesis if neededQT prolongation

Prognosis / Complications

  • Outcomes tied to emergency and timeliness of care

Patient Education / Counseling

  • Explain red flags and when to seek emergent care.
  • Reinforce medication adherence and follow-up plan.

References

  1. BLUE Protocol — Link