USMLE Prep - Medical Reference Library

Epistaxis — Anterior and Posterior Management

System: Otolaryngology • Reviewed: Aug 31, 2025 • Step 1Step 2Step 3

Synopsis:

Control bleeding with firm compression, topical vasoconstrictor and anesthetic, cautery for visible anterior source, and packing when needed; manage posterior bleeds with packing and specialty support.

Key Points

  • Stabilize ABCs; begin targeted evaluation without delaying life-saving therapy.
  • Use system-specific risk tools to guide testing and disposition.
  • Order high-yield tests first; escalate imaging when indicated.
  • Start evidence-based initial therapy and reassess frequently.

Algorithm

  1. Primary survey and vitals; IV access and monitors.
  2. Focused history/physical; identify red flags and likely etiologies.
  3. Order system-appropriate labs and imaging (see Investigations).
  4. Initiate guideline-based empiric therapy (see Pharmacology).
  5. Reassess response; arrange consultation and definitive management.

Clinical Synopsis & Reasoning

For Epistaxis Anterior Posterior Management, frame the differential by acuity and pathophysiology, then align diagnostics to the leading hypotheses. Prioritize stabilization while obtaining high‑yield studies such as CBC (Baseline hematology), BMP (Electrolytes/renal). Incorporate bedside imaging and targeted labs to define severity and identify complications; synthesize results with clinical trajectory to refine the working diagnosis and disposition needs.


Treatment Strategy & Disposition

Initiate disease‑directed therapy alongside supportive care, titrating to objective response. Pharmacologic options commonly include Analgesia/Antipyretics. Use validated frameworks (e.g., Adjuncts and Considerations) to guide escalation and site of care. Address precipitating factors, de‑escalate empiric therapies with data, and arrange follow‑up for monitoring and risk‑factor modification; admit patients with instability, high risk of deterioration, or needs for close monitoring.


Epidemiology / Risk Factors

  • Risk factors vary by condition and patient profile

Investigations

TestRole / RationaleTypical FindingsNotes
CBCBaseline hematologyAbnormal counts
BMPElectrolytes/renalDerangements

Adjuncts and Considerations

TopicTip
AnticoagulationReverse or hold when appropriate
Prophylactic antibioticsConsider for prolonged packing per local policy
AftercareHumidification and saline spray

Pharmacology

MedicationMechanismOnsetRole in TherapyLimitations
Oxymetazoline (topical)α-agonist vasoconstrictorMinutesFirst-line anterior bleedsRebound congestion
Tranexamic acid (topical)AntifibrinolyticMinutesAdjunct for persistent bleedingThrombosis risk (low topical)

Prognosis / Complications

  • Prognosis depends on severity, comorbidities, and timeliness of care

Patient Education / Counseling

  • Explain red flags and when to seek emergent care.
  • Reinforce medication adherence and follow-up plan.

Notes

Check blood pressure and review anticoagulants and antiplatelets. Educate on avoiding nose picking and heavy exertion for several days.


References

  1. AAO HNS Epistaxis Guidance — Link
  2. Emergency Otolaryngology References — Link