USMLE Prep - Medical Reference Library

Pyloric Stenosis - Ultrasound Diagnosis and Preoperative Resuscitation

System: Pediatrics • Reviewed: Aug 31, 2025 • Step 1Step 2Step 3

Synopsis:

Projectile non bilious vomiting and weight loss in young infants suggest pyloric stenosis; confirm with ultrasound, correct dehydration and electrolytes, and arrange pyloromyotomy.

Key Points

  • Stabilize ABCs; begin targeted evaluation without delaying life-saving therapy.
  • Use system-specific risk tools to guide testing and disposition.
  • Order high-yield tests first; escalate imaging when indicated.
  • Start evidence-based initial therapy and reassess frequently.

Algorithm

  1. Primary survey and vitals; IV access and monitors.
  2. Focused history/physical; identify red flags and likely etiologies.
  3. Order system-appropriate labs and imaging (see Investigations).
  4. Initiate guideline-based empiric therapy (see Pharmacology).
  5. Reassess response; arrange consultation and definitive management.

Clinical Synopsis & Reasoning

For Pyloric Stenosis Ultrasound Resuscitation, frame the differential by acuity and pathophysiology, then align diagnostics to the leading hypotheses. Prioritize stabilization while obtaining high‑yield studies such as CBC (Baseline hematology), BMP (Electrolytes/renal). Incorporate bedside imaging and targeted labs to define severity and identify complications; synthesize results with clinical trajectory to refine the working diagnosis and disposition needs.


Treatment Strategy & Disposition

Initiate disease‑directed therapy alongside supportive care, titrating to objective response. Pharmacologic options commonly include Analgesia/Antipyretics. Use validated frameworks (e.g., Typical Lab Pattern) to guide escalation and site of care. Address precipitating factors, de‑escalate empiric therapies with data, and arrange follow‑up for monitoring and risk‑factor modification; admit patients with instability, high risk of deterioration, or needs for close monitoring.


Epidemiology / Risk Factors

  • Risk factors vary by condition and patient profile

Investigations

TestRole / RationaleTypical FindingsNotes
CBCBaseline hematologyAbnormal counts
BMPElectrolytes/renalDerangements

Typical Lab Pattern

FindingExplanation
Hypochloremia and metabolic alkalosisVomiting gastric acid
HypokalemiaRenal loss and alkalosis shift
HemoconcentrationDehydration

Pharmacology

MedicationMechanismOnsetRole in TherapyLimitations
Lorazepam (pre-procedure)GABA-A agonismHoursClaustrophobia/anxiety during ultrasoundSedation
Prednisone + diphenhydramine (premed)Steroid + H1 blockerHoursOnly for prior contrast reactionHyperglycemia/sedation

Prognosis / Complications

  • Prognosis depends on severity, comorbidities, and timeliness of care

Patient Education / Counseling

  • Explain red flags and when to seek emergent care.
  • Reinforce medication adherence and follow-up plan.

Notes

Place NG tube if persistent vomiting and aspiration risk. Document urine output and clinical improvement before anesthesia.


References

  1. AAP surgical neonatal emesis resources — Link
  2. Pediatric surgery and radiology criteria references — Link