USMLE Prep - Medical Reference Library

Spontaneous Pneumothorax — Adult Management

System: Pulmonology • Reviewed: Aug 31, 2025 • Step 1Step 2Step 3

Synopsis:

Primary small events may be observed with oxygen; large or symptomatic events need aspiration or chest tube; secondary pneumothorax favors admission and tube with oxygen.

Key Points

  • Stabilize ABCs; begin targeted evaluation without delaying life-saving therapy.
  • Use system-specific risk tools to guide testing and disposition.
  • Order high-yield tests first; escalate imaging when indicated.
  • Start evidence-based initial therapy and reassess frequently.

Algorithm

  1. Primary survey and vitals; IV access and monitors.
  2. Focused history/physical; identify red flags and likely etiologies.
  3. Order system-appropriate labs and imaging (see Investigations).
  4. Initiate guideline-based empiric therapy (see Pharmacology).
  5. Reassess response; arrange consultation and definitive management.

Clinical Synopsis & Reasoning

For Spontaneous Pneumothorax Management, frame the differential by acuity and pathophysiology, then align diagnostics to the leading hypotheses. Prioritize stabilization while obtaining high‑yield studies such as CXR (Infection/edema/PTX), ABG/VBG (Oxygenation/ventilation), CT chest (indicated) (PE/other). Incorporate bedside imaging and targeted labs to define severity and identify complications; synthesize results with clinical trajectory to refine the working diagnosis and disposition needs.


Treatment Strategy & Disposition

Initiate disease‑directed therapy alongside supportive care, titrating to objective response. Pharmacologic options commonly include SABA, SAMA, Systemic steroids, Antibiotics (if indicated). Use validated frameworks (e.g., Disposition Snapshot) to guide escalation and site of care. Address precipitating factors, de‑escalate empiric therapies with data, and arrange follow‑up for monitoring and risk‑factor modification; admit patients with instability, high risk of deterioration, or needs for close monitoring.


Epidemiology / Risk Factors

  • Smoking/chronic lung disease; infections or immobility (VTE)

Investigations

TestRole / RationaleTypical FindingsNotes
CXRInfection/edema/PTXConsolidation/effusion/PTX
ABG/VBGOxygenation/ventilationHypoxemia/hypercapnia
CT chest (indicated)PE/otherFindings vary

Disposition Snapshot

ScenarioDisposition
Small primary and stableObserve and outpatient follow up
Large primaryAspiration or chest tube; often ED observation
SecondaryChest tube and admission

Pharmacology

MedicationMechanismOnsetRole in TherapyLimitations
High-flow oxygenNitrogen washoutMinutesSmall non-tension PTXO2 toxicity (rare)
Needle decompression/Chest tubeN/AImmediateTension PTX/large PTXInfection/bleeding

Prognosis / Complications

  • Depends on severity/oxygenation; respiratory failure risk

Patient Education / Counseling

  • Explain red flags and when to seek emergent care.
  • Reinforce medication adherence and follow-up plan.

Notes

Avoid air travel and diving until cleared. Use clinical judgment with size thresholds which vary across guidelines.


References

  1. BTS Pleural Disease Guideline — Pneumothorax — Link
  2. CHEST/ACCP Pleural Guidelines — Link