Key Points
            - Use the highest‑yield diagnostic test early; do not let testing delay time‑critical therapy.
- Set objective targets and reassess frequently.
- Plan definitive source control or disease‑specific therapy when indicated; document follow‑up and patient education.
                                        Algorithm
            - High suspicion → call urology and proceed to OR; do not delay for imaging.
- Attempt manual detorsion if skilled and rapid OR not available.
- Perform bilateral orchiopexy; counsel on fertility and recurrence prevention.
                                        Clinical Synopsis & Reasoning
            Acute unilateral testicular pain with high-riding transverse testis and absent cremasteric reflex. Do not delay for imaging—attempt manual detorsion if trained (“open book”) and arrange immediate surgical exploration with bilateral orchiopexy.
                                        Treatment Strategy & Disposition
            Stabilize ABCs. Initiate guideline‑concordant first‑line therapy with precise dosing and continuous monitoring. Escalate to advanced/procedural interventions based on explicit failure criteria. Define ICU, step‑down, and ward disposition triggers; involve specialty teams early.
                                        Epidemiology / Risk Factors
            - Risk varies by comorbidity and precipitants; see citations for condition‑specific data.
                                        Investigations
            
              
                | Test | Role / Rationale | Typical Findings | Notes | 
|---|
                
                  | Clinical exam (cremasteric reflex) | Diagnosis | Absent reflex, high-riding testis | Key sign | 
| Color Doppler ultrasound (if diagnosis uncertain) | Adjunct | Absent/increased flow patterns | Do not delay OR in high suspicion | 
| Urinalysis (rule out epididymitis) | Differential | Often normal in torsion | — | 
                
              
             
                                        High-Risk & Disposition Triggers
            
              
                | Trigger | Why it matters | Action | 
|---|
                
                  | Pain onset >6 h or recurrent torsion | Viability declining | Immediate OR; do not delay for imaging | 
| Bilateral symptoms/anomalies | Future fertility | Fix both sides | 
| Infectious mimic uncertain | Diagnostic delay risk | Urology evaluation; do not anchor on epididymitis | 
| Adolescent with retractile testis | Higher risk | Counseling and follow-up | 
| Delayed presentation or transfer | Worse outcomes | Direct-to-OR protocols | 
                
              
             
                                        Pharmacology
            
              
                | Medication/Intervention | Mechanism | Onset | Role in Therapy | Limitations | 
|---|
                
                  | Manual detorsion (medication-assisted) | Temporizing | Immediate | Pain relief and reperfusion | Not definitive; confirm in OR | 
| Urgent surgical exploration with bilateral orchiopexy | Definitive | Immediate | Fix both testes | Maximize salvage | 
| Analgesia/antiemetics | Supportive | Minutes | Comfort | — | 
                
              
             
                                        Prognosis / Complications
            - Outcome depends on timeliness of diagnosis and definitive therapy; monitor for complications.
                                        Patient Education / Counseling
            - Provide red‑flag education, adherence guidance, and explicit return precautions; arrange timely specialty follow‑up.
                  
        
                  References
                      - AUA guidance on acute scrotum and testicular torsion — Link