Key Points
- Use the highest‑yield diagnostic test early; do not let testing delay time‑critical therapy.
- Set objective targets and reassess frequently.
- Plan definitive source control or disease‑specific therapy when indicated; document follow‑up and patient education.
Algorithm
- Assess airway; consult ENT if difficult airway or spread suspected.
- Perform needle aspiration or I&D with suction and local anesthesia; send culture if needed.
- Start IV antibiotics; transition to PO for 10–14 days when improved; arrange follow‑up.
- Educate on recurrence and tonsillectomy indications in recurrent cases.
Clinical Synopsis & Reasoning
Severe unilateral sore throat with trismus, muffled ‘hot potato’ voice, and uvular deviation. Secure airway if threatened, drain (needle aspiration/incision and drainage), and start antibiotics covering streptococci and oral anaerobes; steroids can reduce pain/edema.
Treatment Strategy & Disposition
Stabilize ABCs. Initiate guideline‑concordant first‑line therapy with precise dosing and continuous monitoring. Escalate to advanced/procedural interventions based on explicit failure criteria. Define ICU, step‑down, and ward disposition triggers; involve specialty teams early.
Epidemiology / Risk Factors
- Risk varies by comorbidity and precipitants; see citations for condition‑specific data.
Investigations
| Test | Role / Rationale | Typical Findings | Notes |
|---|---|---|---|
| Clinical exam ± intraoral ultrasound | Diagnosis | Peritonsillar collection | Ultrasound aids localization |
| CT neck with contrast (selected) | Extent | Deep neck spread | Use if uncertain/complications |
| Culture of aspirate (optional) | Pathogen ID | Strep pyogenes, anaerobes | Tailor therapy |
Pharmacology
| Medication/Intervention | Mechanism | Onset | Role in Therapy | Limitations |
|---|---|---|---|---|
| Ampicillin‑sulbactam 3 g IV q6h or Clindamycin 600–900 mg IV q8h | Antibiotics | Hours | First‑line | PO step‑down amox‑clav or clinda |
| Dexamethasone 10 mg IV/PO (single dose) | Anti‑inflammatory | Hours | Symptom relief | Adjunct |
| Analgesia and hydration | Supportive | Immediate | Pain control | — |
Prognosis / Complications
- Outcome depends on timeliness of diagnosis and definitive therapy; monitor for complications.
Patient Education / Counseling
- Provide red‑flag education, adherence guidance, and explicit return precautions; arrange timely specialty follow‑up.
References
- AAO‑HNS guidance and ENT reviews on peritonsillar abscess — Link